There are 33 wild orchids listed in the national first-class plant protection catalog of China， belonging to several genera including Paphiopedilum Pfitzer， Cypripedium L.， Cymbidium Sw.， Dendrobium Sw.， Phalaenopsis Blume， and Calanthe R. Br.. These species have important ornamental and medicinal value. The registration status of hybrids， their parents selection， pollination and sowing time selection， intergeneric hybridization progress and problems in hybrid breeding of these species have been reviewed. Based on the current breeding situation future breeding directions are proposed. To date， 3611 hybrids with the national first-class wild orchids as parents have been registered in Royal Horticultural Society. The top ten species of hybrids are Paph. spp.， including Paph. bellatulum （Rcnb. F.） Stein.， Paph. insigne （Lindl.） Pfitz. and Paph. spicerianum （H. G. Reichenbach） Pfitzer.， followed by Cymb. Insigne Rolfe. However， no hybrid has been registered with Paph. erythroanthum Z. J. Liu，X. Y. Liao & S. R. Lan， Paph. guangdongense Z. J. Liu & L. J. Chen， Paph. notatisepalum Z. J. Liu，M. Wang & S. R. Lan， and Cypr. subtropicum S. C. Chen & K. Y. Lang as parents. There are few hybrids with Paph. hangianum Perner & O. Gruss， Dend. flexicaule Z. H. Tsi， Dend. huoshanense C. Z. Tang et S. J. Cheng， Cymb. wenshanense Y. S. Wu et F. Y. Liu as parents， although these species are all excellent with potential breeding value. To improve the utilization of wild orchid germplasm resources in future breeding， we propose to make full use of these wild germplasm resources in intergeneric hybridization， in combination with molecular marker assisted selection technology. This article can provide reference for the hybrid breeding of the national first-class wild orchids， and provide support for the innovation of orchid germplasm resources and the sustainable development of the orchid industry.