MADS-box is an important transcription factor in plants， and its family members have a typical MIKC structure， highly conserved N-terminal MADS， and less conserved I domains and C-terminals. MADS-box genes are widely expressed in the roots， stems， leaves， flowers， buds and other trophic tissue parts of plants， and are involved in regulating the flowering time， flower development， seed development and abiotic stress response. In recent years， researches have shown that the expression patterns of different MADS-box genes are distinct， and their functions are also quite different. This review introduces the structure and classification of soybean MADS-box gene family， and summarizes the research progress of related members of MADS-box genes in ABCDE model， such as SVP， SOC1， FLC and other genes in the flower development. Finally， the research on soybean MADS-box is prospected， which provides an essential information for further utilization of such transcription factor genes for soybean genetic improvement and germplasm innovation in the future.