Based on more than 20 years of wheat big grain and spike weight resource innovation research,we selected 256 big grain germplasm accounting for 8.9%,93 rare big grain germplasm accouting for 3.2%,8 large grain resources accounting for 0.3% of total 2878 wheat resources in 2000-2006.There were 176 resources with single spike weight from 2g to 2.49g accounting for 0.3%,83 germplasm with single spike weight from 2.5g to 2.99g accouting for 2.88%,19 valuable germplasm with single spike weight of more than 3 g accouting for 0.66%.The developed innovation strategy for big grain and weighty spike germplasm included ideal plant shape trait with large grain and spike weight,secure yield trait with big grain and weighty spike trait,excellent quality traits with big grain and weighty spike trait,combination of ordinary technique and modern biotechnology.Through innovation,excellent large grain and weighty spike middle materials breeding could supply fine gene resources and improve the development for super-wheat breeding.