Screening for grain smut resistant genotypies of Foxtail millet germplasm were carried out on 2050 from different regions of China with artificia infcected fungus.Activities and isoenzyme of peroxidase(POX) between resistant and sensitive genotypies were analysed in different period.The results showed that resistance of Foxtail millet varieties to grain smut were different.After affected with Grain smut,resistand varieties had a higher POX activities than that of sensitive ones.Peroxidase isoenzyme can be used of a genetic(mark.)