As the reproductive organ of angiosperms, the flower is a vital part of plants, which is a prime basis for plant evolution and classification study. Flower development is affected by factors, and genes, as the important factors among them, play a vital role in the whole process, and the function of genes in flower development has always been a hot spot of research. In this paper, we reviewed the regulatory roles of MADS-box, related members of the AP2/ERF gene family, and genes such as NAP, SPL, TGA, PAN and WOX in floral organogenesis, which provide further insight into the roles of the genes in the regulation of floral development in various plants.