In order to further understand the genetic mechanism on the resistance to turnip mosaic virus (TuMV) in elite radish germplasm, the inheritance was analyzed by applying the joint segregation analysis of a mixed genetic model of major gene plus polygene in six generations (P1, P2, F1, B1, B2 and F2) from the cross between highly resistant inbred line ‘Q07-12’ (P1) and highly susceptible line ‘KB07-10’(P2). The inheritance of resistance to TuMV was fitted by the two major genes plus polygenes mixed model (E model). In B1, B2 and F2 populations , the estimated heritability of major genes were 89 %,55 % and 95 %, respectively. The heritability of polygenes were 0, 40.9 % and 0 respectively . The environmental factors had small effect on the resistance to TuMV in radish. These results indicate that the elite resistant radish germplasm is of value in radish genetic improvement, and provide the genetic basis for improving the efficiency of breeding for TuMV-resistance.