Guizhou HE Rice (O. Sativa L.), one of the valuable rice germplasm resources in China, is regarded as a special ecotype of rice. Protection and utilization of this resource is of great significance. In a variety of ways, the investigation was carried out in 15 Dong villages in 6 townships of Liping County, Guizhou Province. The survey collected accessions of 44 resources. Liping County, considered a main producing area of HE Rice, is one of the birthplaces of waxy food circle. Diverse genetic resources and wealthy traditional cultures are still well reserved in the area. As a symbol of the minority culture, the utilization, protection and inheritance of the rice were closely related to the local culture including Dong people’s daily diet, religious ceremonies and festivals. Countermeasures and suggestions were proposed for the protection and utilization of HE Rice resources.